Obesity

Feasibility and efficacy of adding high-intensity interval training to a multidisciplinary lifestyle intervention in children with obesity—a randomized controlled trial

Int J Obes (Lond)Published Randomised controlled trial

Authors' conclusion

Adding a 12-week HIIT program did not further augment the positive effects of a 12-month lifestyle intervention on BMI z-score. Adding HIIT improved HRQOL after 3 months, but reduced HRQOL at 12 months. Implementation of HIIT in community-based settings was feasible and showed positive effects on adherence to the lifestyle intervention.

Study context

Population
Children and adolescents with obesity, Denmark
Participants
173 children
Comparison
12-month lifestyle intervention plus 12-week high-intensity interval training (HIIT) vs lifestyle intervention alone
Primary endpoint
Change in BMI z-score

Primary result

As reported in the abstract

HIIT vs ControlMD (95% CI)P value
3 months; did not differ
0.01(−0.09 to 0.12)
P = 0.82
12 months; did not differ
0.06(−0.07 to 0.19)
P = 0.34

Further findings

OutcomeValuesDifference (CI)P value
HRQOL (PedsQL Child)HIITvs Control3 months, total-score; greater increase with HIIT2.73 (0.01–5.44)P = 0.05
HRQOL (PedsQL Child)HIITvs Control3.85 (0.96–6.74)P < 0.01
OutcomeValuesDifference (CI)P value
HRQOL (PedsQL Child)Between HIIT and Control · 12 months, physical-score; reduced with HIIT6.89 (10.97–2.83)P < 0.01
HIIT attendance · 3 monthsHIIT 68.0 ± 23.2 %
  • Health-related quality of life (HRQOL) (PedsQL Child): 3 months, psychosocial health-score; greater increase with HIIT

BMI z-score reduction across randomization

Reduction at 3 months
0.11 (CI: 0.17; 0.06, P < 0.01)
Reduction at 12 months
0.20 (CI: 0.26;0.14, P < 0.01)

Dropout

Dropout at 3 months, HIIT vs control
7.8% vs. 20.5%
Dropout at 12 months, HIIT vs control
26.5% vs 48.2%

Waist circumference and blood pressure

No group differences or changes over time

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Feasibility and efficacy of adding high-intensity interval training to a multidisciplinary lifestyle intervention in children with obesity—a randomized controlled trial. Int J Obes (Lond). Published 10 October 2024. doi:10.1038/s41366-024-01645-w

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