Obesity

High-intensity interval training improves myocardial work and cardiac function in women with obesity: a randomized controlled study

Int J Obes (Lond)Published Randomised controlled trial

Authors' conclusion

HIIT and MICT both improved myocardial deformation in women with obesity. However, only HIIT improved myocardial efficiency

Study context

Population
Women with obesity (age 28 ± 5 years, BMI 35.03 ± 3.19 kg/m²)
Participants
25 women
Comparison
High-intensity interval training (HIIT) vs moderate-intensity continuous training (MICT) for 8 weeks
  • HIITn = 11
  • MICTn = 14reference

Primary result

As reported in the abstract

Myocardial efficiency (myocardial work (MW) indices, speckle tracking echocardiography) · 8 weeks
HIIT reduced global wasted work (GWW), d = 0.64
p = 0.042
HIIT increased global work efficiency (GWE), d = 0.83
p = 0.005

Further findings

Myocardial deformation: LV global longitudinal strain (GLS), left atrial (LA) contraction, LA conduit, LA reservoir, LA stiffness · 8 weeks

LV GLS reduced with HIIT
P = 0.017
LV GLS reduced with MICT
P = 0.023
LA contraction reduced with both
P < 0.001
LA conduit reduced with both
P = 0.002
LA reservoir reduced with HIIT
P = 0.003
LA reservoir reduced with MICT
P < 0.001
LA stiffness reduced with HIIT
P = 0.004
LA stiffness reduced with MICT
P = 0.031

Original publication

High-intensity interval training improves myocardial work and cardiac function in women with obesity: a randomized controlled study. Int J Obes (Lond). Published 10 July 2026. doi:10.1038/s41366-026-02158-4

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