High-intensity interval training improves myocardial work and cardiac function in women with obesity: a randomized controlled study
Authors' conclusion
HIIT and MICT both improved myocardial deformation in women with obesity. However, only HIIT improved myocardial efficiency
Study context
- Population
- Women with obesity (age 28 ± 5 years, BMI 35.03 ± 3.19 kg/m²)
- Participants
- 25 women
- Comparison
- High-intensity interval training (HIIT) vs moderate-intensity continuous training (MICT) for 8 weeks
- HIITn = 11
- MICTn = 14reference
Primary result
As reported in the abstract
Myocardial efficiency (myocardial work (MW) indices, speckle tracking echocardiography) · 8 weeks
- HIIT reduced global wasted work (GWW), d = 0.64
- p = 0.042
- HIIT increased global work efficiency (GWE), d = 0.83
- p = 0.005
Further findings
Myocardial deformation: LV global longitudinal strain (GLS), left atrial (LA) contraction, LA conduit, LA reservoir, LA stiffness · 8 weeks
- LV GLS reduced with HIIT
- P = 0.017
- LV GLS reduced with MICT
- P = 0.023
- LA contraction reduced with both
- P < 0.001
- LA conduit reduced with both
- P = 0.002
- LA reservoir reduced with HIIT
- P = 0.003
- LA reservoir reduced with MICT
- P < 0.001
- LA stiffness reduced with HIIT
- P = 0.004
- LA stiffness reduced with MICT
- P = 0.031
Original publication
High-intensity interval training improves myocardial work and cardiac function in women with obesity: a randomized controlled study. Int J Obes (Lond). Published 10 July 2026. doi:10. 1038/ s41366-026-02158-4
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