Effects of different exercise modalities and doses on glycated hemoglobin in patients with type 2 diabetes mellitus and overweight or obesity: a systematic review and Bayesian multilevel network meta-analysis
Authors' conclusion
Structured exercise interventions were associated with reductions in HbA1c in this population. HIIT and combined training showed the most favorable estimates, but the low to very low certainty of evidence and moderate heterogeneity require cautious interpretation.
Study context
- Population
- Adults with T2D and overweight or obesity; RCTs from PubMed, Web of Science, Embase and Cochrane Library to February 2026
- Participants
- 5,022 adults67 studies
- Comparison
- Exercise modalities vs control
- Outcome
- HbA1c
Methodological detailsmeta-regression
- Meta-regression
Pooled result
As reported in the abstract
Each group vs controlMD, % (95% CrI)
HIITCrI; largest reduction
−0.73(−0.96 to −0.49)
Combined trainingCrI
−0.54(−0.70 to −0.38)
Further pooled results
Exercise dose (exploratory study-level meta-regression)
- No single optimal dose identified; greater uncertainty at exposure extremes
Original publication
Effects of different exercise modalities and doses on glycated hemoglobin in patients with type 2 diabetes mellitus and overweight or obesity: a systematic review and Bayesian multilevel network meta-analysis. Diabetes Res Clin Pract. Published 24 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →