Pediatric endocrinology

Evaluation of quality of life in children with precocious puberty

Clin Endocrinol (Oxf)Published Case-control study

Authors' conclusion

Unlike previous studies, in this study the effects of sociodemographic characteristics and whether treatment was initiated or not on quality of life were investigated. Although the scale scores of the CPP group were lower than the PT and control group, there was no statistically significant difference, indicating that quality of life was not negatively affected in the CPP group receiving treatment.

Study context

Population
Children with central precocious puberty (CPP) or premature thelarche (PT) and healthy children, with their parents
Participants
193 children
Comparison
CPP vs PT vs healthy controls
  • CPPn = 59
  • PTn = 53
  • Controln = 81reference
Outcome
Quality of life (PedsQL)

Main finding

As reported in the abstract

PedsQL total scale score

CPP

78.10

± 17.13

PT

79.35

± 11.54

Control

79.52

± 14.65

P > 0.05

Observational data: associations, not effects.

Further findings

OutcomeCPPPTControl
PedsQL psychosocial health summary score78.86 ± 16.8379.40 ± 12.5479.94 ± 14.94
PedsQL physical health summary score75.81 ± 20.6979.41 ± 15.0478.25 ± 17.52

PedsQL psychosocial health summary score

No statistical difference (p > .05)

PedsQL physical health summary score

No statistical difference (p > .05)

Parent-administered scale

Scores similar in the three groups

Sociodemographic data

No difference between CPP, PT and control groups (p > .05)

Original publication

Evaluation of quality of life in children with precocious puberty. Clin Endocrinol (Oxf). Published 20 February 2024. doi:10.1111/cen.15033

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