Type 2 & other diabetes

Estimated Sustainable Cost-Based Prices for Diabetes Medicines

JAMA Netw OpenPublished Economic evaluation

An erratum to this article was published (JAMA Netw Open, 1 Apr 2024 ↗)

Authors' conclusion

High prices limit access to newer diabetes medicines in many countries. The findings of this study suggest that robust generic and biosimilar competition could reduce prices to more affordable levels and enable expansion of diabetes treatment globally.

Study context

Population
Insulins, SGLT2i and GLP-1 RA; current prices in 13 countries of different income levels and regions, collected January 202313 countries
Comparison
Estimated sustainable cost-based prices (CBPs) vs current market prices of insulins, SGLT2i and GLP-1 RA
Outcome
Estimated CBPs; lowest current market prices (2023 US dollars)
Methodological detailscost-of-manufacturing modelling, weighted least-squares regression model
  • Cost-of-manufacturing modelling
  • Weighted least-squares regression model

Main finding

As reported in the abstract

Estimated CBPs
Insulin, reusable pen, basal-bolus regimen: human insulin
$96 per year
Insulin, reusable pen, basal-bolus regimen: insulin analogues
$111 per year
Twice-daily injections of mixed human insulin
$61 per year
Once-daily basal insulin (T2D): human insulin
$50 per year
Once-daily basal insulin (T2D): insulin analogues
$72 per year
SGLT2i (except canagliflozin)
$1.30 to $3.45 per month
Canagliflozin
$25.00-$46.79
GLP-1 RA
$0.75 to $72.49 per month

Original publication

Estimated Sustainable Cost-Based Prices for Diabetes Medicines. JAMA Netw Open. Published 4 March 2024. doi:10.1001/jamanetworkopen.2024.3474

Composed by AI from the published abstract and checked against it. How Briefs are made →

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