Efficacy of high‐intensity interval training in individuals with type 2 diabetes mellitus: An umbrella review of systematic reviews and meta‐analyses
Authors' conclusion
This umbrella review supports HIIT as an efficacious exercise strategy for improving glycaemic control and certain relevant cardiometabolic health outcomes in individuals with T2DM.
Study context
- Population
- Individuals with T2D10 SRs with MAs, 76 primary studies
- Participants
- 2,954 individuals
- Comparison
- High-intensity interval training (HIIT) vs moderate-intensity continuous training (MICT) and/or non-exercise control
- Outcome
- Glycaemic control and other clinically relevant cardiometabolic health outcomes
Methodological detailsPRIOR guideline, AMSTAR-2 quality assessment, seven databases searched until August 2024, Literature search, data extraction and quality assessment conducted independently by two reviewers
- PRIOR guideline
- AMSTAR-2 quality assessment
- Seven databases searched until August 2024
- Literature search, data extraction and quality assessment conducted independently by two reviewers
Pooled result
As reported in the abstract
Range across reviews
- HIIT vs control (CON)
- weighted mean difference, HbA1c −0.83% to −0.39%
- HIIT vs CON
- weighted mean difference, cardiorespiratory fitness 3.35-6.38 mL/kg/min
- HIIT vs MICT
- weighted mean difference, HbA1c −0.37% to −0.07%
- HIIT vs MICT
- weighted mean difference, cardiorespiratory fitness 1.68-4.12 mL/kg/min
Further pooled results
Other glycaemic parameters (fasting blood glucose, fasting blood insulin, HOMA-IR)
- HIIT also effective in improving fasting blood glucose, fasting blood insulin and HOMA-IR
Body composition, lipid profiles and blood pressure
- Improvement in body composition, lipid profiles and blood pressure observed following HIIT
Methodological quality (AMSTAR-2)
- Most systematic reviews received moderate to low AMSTAR-2 score
Original publication
Efficacy of high‐intensity interval training in individuals with type 2 diabetes mellitus: An umbrella review of systematic reviews and meta‐analyses. Diabetes Obes Metab. Published 5 February 2025. doi:10.
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