Effects of time-restricted eating on glycemic control and variability in individuals with overweight/obesity and prediabetes: A secondary analysis of the Restricted Eating Time (RESET) randomized controlled trial
Authors' conclusion
TRE may have a small short-term beneficial effect on nighttime glucose levels in adults with prediabetes.
Study context
- Population
- Adults with overweight/obesity and prediabetesprediabetes subset
- Participants
- 46 adults
- Comparison
- 10-hour time-restricted eating (TRE) vs control
- TREn = 20
- Controln = 26reference
Methodological detailsexploratory analysis
- Exploratory analysis
Primary result
As reported in the abstract
Fasting glucose and HbA1c · 6 weeks and 3 months
- No between-group differences in fasting glucose or HbA1c after 6 weeks and 3 months
- Exploratory analysis
Further findings
| Outcome | Difference (mmol/L) (CI) | |
|---|---|---|
| Nighttime average sensor glucose · 6 weeks | −0.3 (−0.6 to −0.1) | |
| Nighttime average sensor glucose · 3 monthsEffect not maintained | −0.1 (−0.4 to 0.2) | |
| −1−0.500.5Difference, mmol/L (linear scale) |
24-hour and daytime CV · 6 weeks and 3 months
- 24-hour and daytime CV reduced within TRE after 6 weeks but not after 3 months
Original publication
Effects of time-restricted eating on glycemic control and variability in individuals with overweight/obesity and prediabetes: A secondary analysis of the RESET randomized controlled trial. Diabetes Res Clin Pract. Published 21 April 2026. doi:10.
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