Age- and sex-specific trends in dementia mortality among people with and without diabetes: a multi-country population-based analysis
Authors' conclusion
Increases in dementia mortality were observed for those aged 80 years and above and were most marked for people with diabetes.
Study context
- Population
- Individuals with and without diabetes in Australia, Canada (Alberta and Ontario), France, Denmark, Finland and Scotland, 2000 to 2023
- Exposure
- People with vs without diabetes
- Outcome
- Age- and sex-specific time trends in mortality with dementia as the underlying cause of death, at 60, 70, 80 and 90 years of age
Methodological detailsaggregated registry and administrative data, Poisson regression
- Aggregated registry and administrative data
- Poisson regression
Main finding
As reported in the abstract
Dementia mortality trends · 2000 to 2023
| Group | Value | Person-years of follow-up |
|---|---|---|
| Diabetes | 114,559 events | over 42 million |
| No diabetes | 589,706 events | over 244 million |
Value
Diabetes114,559 events
No diabetes589,706 events
Person-years of follow-up
Diabetesover 42 million
No diabetesover 244 million
- At 80 and 90 years: increases in most jurisdictions, per 5 years
- 7.6% to 42.4%
Observational data: associations, not effects.
Further findings
Mortality from dementia subtypes (e.g. Alzheimer's disease and vascular dementia), aged 40-89 years
- Increased over time, with greater increases for individuals with diabetes, specifically in Australia and Scotland
Original publication
Age- and sex-specific trends in dementia mortality among people with and without diabetes: a multi-country population-based analysis. Diabetologia. Published 21 April 2026. doi:10. 1007/ s00125-026-06725-2
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