Time-Restricted Eating in Adults With Metabolic Syndrome : A Randomized Controlled Trial
Primary result · HbA1cResult — go to the resultDifference −0.10 % 95% CI −0.19% to −0.003%Authors' conclusion
Personalized 8- to 10-hour TRE is an effective practical lifestyle intervention that modestly improves glycemic regulation and may have broader benefits for cardiometabolic health in adults with metabolic syndrome on top of SOC pharmacotherapy and nutritional counseling.
Study context
- Population
- Adults with metabolic syndrome including elevated fasting glucose or hemoglobin A1c (HbA1c) (pharmacotherapy allowed); clinical research institute108 completed
- Comparison
- Standard-of-care (SOC) nutritional counseling plus personalized 8- to 10-hour time-restricted eating (TRE) vs SOC alone
- Primary endpoint
- HbA1c, fasting glucose, fasting insulin, HOMA-IR and CGM glycemic assessments
- Follow-up
- 3 months
Methodological detailsTiming of dietary intake tracked in real time with myCircadianClock smartphone app
- Timing of dietary intake tracked in real time with myCircadianClock smartphone app
Primary result
HbA1c
Difference
−0.10 %
95% CI −0.19% to −0.003%
TREvs SOC
difference −0.10 % (95% CI −0.19% to −0.003%)
As reported in the abstract
Safety
- No major adverse events
Original publication
Time-Restricted Eating in Adults With Metabolic Syndrome : A Randomized Controlled Trial. Ann Intern Med. Published 1 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →