Effects of COVID-19 time on the development of pre-impaired glucose tolerance state in children and adolescents with overweight and obesity
Authors' conclusion
During COVID-19 time a higher percentage of children are in the highest range of normal 2 h PG values which is known to be associated with a significant impairment of β-cell function and insulin sensitivity and have higher risk of developing IGT.
Study context
- Population
- Children and adolescents with obesity and overweight who underwent complete evaluation and OGTT
- Participants
- 532 children
- Exposure
- During COVID-19 pandemic vs before
- Outcome
- Distribution of 2 h PG values after OGTT across 3 sub-groups (group 1 <5.55, group 2 5.56–6.60, group 3 6.61–7.72 mmol/L)
Main finding
As reported in the abstract
Distribution of 2 h PG (group 1 / group 2 / group 3)
Before COVID-19
35.6%, 45.9% and 18.5%
During COVID-19
31.1%, 31.1% and 37.8%
P = 0.01
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Group 3 (2 h PG 6.61–7.72 mmol/L): WC, WtHR, fasting glucose, HOMA-IRSignificantly higher with During COVID-19 | all P < 0.05 |
Original publication
Effects of COVID-19 time on the development of pre-impaired glucose tolerance state in children and adolescents with overweight and obesity. Int J Obes (Lond). Published 27 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →