Central obesity and its association with retinal age gap: insights from the UK Biobank study
Authors' conclusion
A significant positive association exists between central obesity and accelerated ageing indexed by retinal age gaps, highlighting the significance of maintaining a healthy body shape.
Study context
- Population
- UK Biobank participants with body mass index (BMI), waist circumference (WC) and qualified retinal imaging data; 55.6% females, mean age 56.8 ± 8.04 years
- Participants
- 35,550 participants
- Exposure
- Anthropometric groups by BMI and waist circumference vs Normal-weight/Normal WC
- Outcome
- Retinal age gap (retinal age minus chronological age)
Methodological detailsUK Biobank
- UK Biobank
Main finding
As reported in the abstract
Retinal age gap (continuous), fully adjusted models
β
0.264
95% CI 0.105–0.424P = 0.001
Overweight/High WC
β
0.226
95% CI 0.082–0.371P = 0.002
Mild obesity/High WC
β
0.273
95% CI 0.081–0.465P = 0.005
Severe obesity/High WC
Observational data: associations, not effects.
Further findings
Retinal age gap as categorical outcome
- Similar findings for anthropometric groups and retinal ageing as a categorical outcome
Original publication
Central obesity and its association with retinal age gap: insights from the UK Biobank study. Int J Obes (Lond). Published 25 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →