Effects of early, late and self-selected time-restricted eating on visceral adipose tissue and cardiometabolic health in participants with overweight or obesity: a randomized controlled trial
Authors' conclusion
These findings suggest that adding TRE, irrespective of eating window timing, offers no additional benefit over a Mediterranean diet alone in reducing VAT. TRE appears to be a safe, well-tolerated and feasible dietary approach for adults with overweight or obesity.
Study context
- Population
- Adults with overweight or obesityrandomized
- Participants
- 197 adults
- Comparison
- Early, late or self-selected time-restricted eating (TRE) plus usual care (UC) vs UC alone
- UCn = 49reference
- Early TREn = 49
- Late TREn = 52
- Self-selected TREn = 47
- Primary endpoint
- VAT changes measured by MRI
- Follow-up
- 12 weeks
Primary result
As reported in the abstract
VAT change
Each group vs UCMD, % (95% CI)P value
Early TRE
−4(−12 to 4)
P = 0.87Late TRE
−6(−13 to 2)
P = 0.31Self-selected TRE
−3(−11 to 5)
P ≥ 0.99- No significant differences in visceral adipose tissue (VAT) changes among the TRE groups
- all P ≥ 0.99
Further findings
- Adherence across TRE groups
- 85-88%
Safety
- Serious adverse events
- 0
- Participants reporting mild adverse events
- 5
Original publication
Effects of early, late and self-selected time-restricted eating on visceral adipose tissue and cardiometabolic health in participants with overweight or obesity: a randomized controlled trial. Nat Med. Published 7 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →