Time‐restricted eating affects human adipose tissue fat mobilization
Authors' conclusion
This study provides insights into the potential benefits of TRE on fat mobilization and may guide the design of future dietary strategies for weight management and metabolic health.
Study context
- Population
- Subcutaneous adipose tissue (AT) from participants with severe obesity
- Participants
- 21 participants
- Comparison
- Early TRE (eTRE) vs delayed TRE (dTRE) vs 24-h fasting vs control in AT culture
- Outcome
- Fat mobilization measured as glycerol release in AT culture
Methodological detailsex vivo human adipose tissue cultures
- Ex vivo human adipose tissue cultures
Main finding
As reported in the abstract
Glycerol release (lipolysis)
P < 0.0001
- eTRE showed higher glycerol mobilization than dTRE over the 24-h window, especially at nighttime/habitual sleep episode
- P < 0.0001
Further findings
Glycerol release by fasting duration, independent of time window
- Glycerol release by fasting duration, independent of time window — Glycerol release increased with fasting duration
- p < 0.0001
Original publication
Time‐restricted eating affects human adipose tissue fat mobilization. Obesity (Silver Spring). Published 28 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →