Time–restricted eating alters the 24‐hour profile of adipose tissue transcriptome in men with obesity
Authors' conclusion
TRE restored 24-hour profiles in hormones, metabolites, and genes controlling transcriptional regulation in SAT, which could underpin its metabolic health benefit.
Study context
- Population
- Men with obesity, age 63 [4] years, BMI 30.5 [2.4] kg/m²
- Participants
- 15 men
- Comparison
- 8 weeks of 10-hour time-restricted eating (TRE) vs baseline
- Outcome
- 24-hour profiles of plasma metabolites, glucoregulatory hormones and subcutaneous adipose tissue (SAT) transcriptome
- Follow-up
- 8 weeks
Methodological detailssingle-group pre-post, 35-hour metabolic ward stay
- Single-group pre-post
- 35-hour metabolic ward stay
Main finding
As reported in the abstract
Genes with rhythmicity altered by TRE
450
Original publication
Time–restricted eating alters the 24‐hour profile of adipose tissue transcriptome in men with obesity. Obesity (Silver Spring). Published 1 August 2022. doi:10.
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