M RI assessment of adipose tissue fatty acid composition in the UK Biobank and its association with diet and disease
Authors' conclusion
This extensive analysis revealed the relationships between adipose tissue FA composition and a range of factors in a diverse population, highlighting the importance of studying body adipose tissue beyond its quantity.
Study context
- Population
- UK Biobank imaging cohort; subcohort following a vegan or an omnivore diet (N = 36) to validate the effect of diet
- Participants
- 33,823 participants
- Outcome
- Fractions of saturated, monounsaturated and polyunsaturated FA (fSFA, fMUFA, fPUFA) in ASAT and VAT, measured by MRI
Methodological detailsUK Biobank imaging cohort, multiecho magnetic resonance imaging (MRI)
- UK Biobank imaging cohort
- Multiecho MRI
Main finding
As reported in the abstract
Adipose tissue FA composition, VAT vs ASAT
- Higher fSFA and fPUFA and lower fMUFA in VAT
- p < 0.00016
Observational data: associations, not effects.
Further findings
Fatty acid (FA) composition by sex
- fMUFA and fPUFA higher in ASAT and lower in VAT for women
- P < 0.00016
FA composition by diet (vegan vs omnivore)
- Vegan participants had lower fSFA in both ASAT and VAT
- P < 0.00016
Associations with disease and anthropometrics
- VAT fSFA and fMUFA significantly associated with disease and anthropometric variables
Original publication
M RI assessment of adipose tissue fatty acid composition in the UK Biobank and its association with diet and disease. Obesity (Silver Spring). Published 25 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →