Effectiveness of Continuous Glucose Monitoring on Glycemic and Metabolic Outcomes in Type 2 Diabetes: A Two-Year Real-World Analysis
Authors' conclusion
Two-year use of CGM in routine care was associated with favorable trends in glycemic control, glycemic stability, self-monitoring behavior, and health care utilization. Long-term CGM integration may be feasible and potentially beneficial across diverse T2D populations, although prospective studies are needed to clarify the causal effects.
Study context
- Population
- Adults with T2D initiating second-generation continuous glucose monitoring (CGM) (FreeStyle Libre 2) at a tertiary care center in Saudi Arabia; mean age 48.7 years, 48.2% female
- Participants
- 222 adults
- Exposure
- Baseline vs 12 and 24 months of sustained CGM use
- CGMn = 222
- Outcome
- HbA1c
- Follow-up
- Baseline to T24
Methodological detailsretrospective chart review, single-centre, tertiary care center, real-world
- Retrospective chart review
- Single-centre
- Tertiary care center
- Real-world
Main finding
As reported in the abstract
HbA1c declined from baseline to T24
8.2% to 7.8%
Observational data: associations, not effects.
Further findings
Glycemic improvements by subgroup (obesity, oral agents only, insulin-based regimens)
- Directionally similar glycemic improvements across subgroups
Body weight · 24 months
- Body weight decreased over 24 months
- ≈2 kg
Safety
- Diabetes-related ED visits at T0
- 5 (2.3%)
- Diabetes-related ED visits at T12
- 2 (0.9%)
- Diabetes-related ED visits at T24
- 1 (0.5%)
Original publication
Effectiveness of Continuous Glucose Monitoring on Glycemic and Metabolic Outcomes in Type 2 Diabetes: A Two-Year Real-World Analysis. J Diabetes Sci Technol. Published 11 May 2026. doi:10.
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