Obesity

Effect of time‐restricted eating on sex hormone levels in premenopausal and postmenopausal females

Obesity (Silver Spring)Published Secondary analysis of an 8-week time-restricted eating (TRE) study

Authors' conclusion

In premenopausal females, androgens and SHBG remained unchanged during TRE, whereas DHEA decreased. In postmenopausal females, estrogens, progesterone, androgens, and SHBG did not change, but DHEA was reduced.

Study context

Population
Adults with obesity on 8-week TRE; men and perimenopausal females excluded
Participants
12 vs 11
Comparison
Premenopausal vs postmenopausal females during TRE
  • Premenopausaln = 12
  • Postmenopausaln = 11
Primary endpoint
Sex steroid levels
Follow-up
8 weeks
Methodological details4- to 6-hour eating window
  • 4- to 6-hour eating window

Primary result

As reported in the abstract

Sex steroids
Dehydroepiandrosterone (DHEA) change, premenopausal
−14% ± 32%
DHEA change, postmenopausal
−13% ± 34%
DHEA decrease, main effect of time
p = 0.03

Further findings

Body weight change · 8 weeks

Premenopausal
−3% ± 2%
Postmenopausal
−4% ± 2%
Main effect of time
P < 0.001
No difference between groups (no group × time interaction)

Original publication

Effect of time‐restricted eating on sex hormone levels in premenopausal and postmenopausal females. Obesity (Silver Spring). Published 6 October 2022. doi:10.1002/oby.23562

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