Type 2 & other diabetes

Eating behavior dimensions and 9-year weight loss maintenance: a sub-study of the Finnish Diabetes prevention study

Int J Obes (Lond)Published Secondary analysis of the Finnish Diabetes Prevention Study randomised trial

Authors' conclusion

Lifestyle intervention with intensive and individually tailored, professional counselling had long-lasting effects on cognitive restraint of eating and body weight in middle-aged participants with overweight and IGT. The mediation analyses suggest that early phase increase in cognitive restraint could have a role in long-term weight loss maintenance. This is important because long-term weight loss maintenance has various health benefits, including reduced risk of T2DM.

Study context

Population
Middle-aged adults (38 men, 60 women) with overweight and impaired glucose tolerance (IGT), Kuopio research center38 men · 60 women
Participants
51 vs 47
Comparison
Intensive individualized lifestyle intervention vs control
  • Interventionn = 51
  • Controln = 47reference
Primary endpoint
Mediation of the intervention effect on body weight by first-year changes in eating behavior dimensions (Three Factor Eating Questionnaire)
Follow-up
9 years
Methodological detailssub-study, single-centre (Kuopio), mediation analysis
  • Sub-study
  • Single-centre (Kuopio)
  • Mediation analysis

Primary result

As reported in the abstract

Mediation of intervention effect on weight loss
  • First-year increases in total, flexible and rigid restraint statistically mediated the impact of intervention on weight loss during the 9-year study

Further findings

OutcomeInterventionControlP value
Change in total cognitive restraint · first year4.6 scores1.7 scoresP < 0.001
Change in flexible restraint · first year1.70.9P = 0.018
Change in rigid restraint · first year1.60.5P = 0.001
Change in body weight · first year−5.2 kg−1.2 kgP < 0.001
Change in total cognitive restraint · 9 years2.6 scores0.1 scoresP = 0.002
Change in rigid restraint · 9 years1.00.4P = 0.004
Change in body weight · 9 years−3.0 kg0.1 kgP = 0.046

Original publication

Eating behavior dimensions and 9-year weight loss maintenance: a sub-study of the Finnish Diabetes prevention study. Int J Obes (Lond). Published 6 May 2023. doi:10.1038/s41366-023-01300-w

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