Gestational diabetes & diabetes in pregnancy
Do WHO criteria for gestational diabetes fit a rural population in Tanzania? – A follow-up study assessing mother and child health six years after a pregnancy diagnosed with gestational diabetes
Authors' conclusion
Despite high prevalence of GDM amongTanzanian women, the diagnosis was not associated with adverse pregnancy outcomes, nor with increased risk of prediabetes or T2D at follow-up. FPG and HbA1c may be poor markers for diabetes in this population, and further follow-up studies with longer time intervals are warranted to evaluate which GDM diagnostic criteria are most optimal for women in rural Tanzania and similar LMIC settings.
Study context
- Population
- Mothers and children from rural north-eastern Tanzania, 6 years after a pregnancy with/without GDM197 mothers · 251 children
- Exposure
- Women with previous GDM vs without GDM
- Outcome
- Prevalence of prediabetes and T2D
- Follow-up
- 6 years after pregnancy
Methodological detailsfollow-up study, rural
- Follow-up study
- Rural
Main finding
As reported in the abstract
- Prediabetes and T2D prevalence similar between women with/without previous GDM
- Previous GDM vs No GDM: P ≥ 0.36
- Previous GDM vs No GDM: P ≥ 0.36
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Prediabetes and T2D, second set of values reported for FPG or HbA1c levels · 6 yearsPrevious GDM vs No GDM · 16.9 % vs. 13.8 % | P = 0.47 |
| Prediabetes and T2D, second set of values reported for FPG or HbA1c levels · 6 yearsPrevious GDM vs No GDM · 1.2 % vs. 0 % | P = 0.47 |
Cardio-metabolic health parameters, perinatal outcomes and child health
- Cardio-metabolic parameters, perinatal outcomes and child health at follow-up similar between women with/without previous GDM
Cardio-metabolic risk markers: prediabetes/T2D vs normal glucose tolerance
- Overall prevalence of prediabetes/T2D high; no differences in other cardio-metabolic risk markers vs normal glucose tolerance
Original publication
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