Diet Quality Scores and Central Precocious Puberty Risk in Chinese Girls: A Case–Control Study
Authors' conclusion
High-quality dietary patterns and an anti-inflammatory diet may contribute to the prevention of CPP in Chinese girls.
Study context
- Population
- Chinese girls with central precocious puberty (CPP) and healthy controls; diet assessed by validated food frequency questionnaire
- Participants
- 112 vs 131
- Comparison
- Girls with CPP vs healthy controls
- CPPn = 112
- Healthy controlsn = 131reference
- Outcome
- Association of diet quality and inflammatory diet scores (C-DII, Chinese Children's Dietary Index (CCDI), Dietary Approaches to Stop Hypertension (DASH), aDASH) with risk of CPP (logistic regression)
Main finding
As reported in the abstract
Diet scores and CPP risk (adjusted)
- Higher Children's Dietary Inflammatory Index (C-DII) scores associated with increased CPP risk
- P for trend = 0.034
- Adjusted Dietary Approaches to Stop Hypertension (aDASH) scores significantly negatively associated with CPP risk
- P for trend = 0.048
Observational data: associations, not effects.
Further findings
- IL-6 positively correlated with CPP risk
- P for trend = 0.006
- Serum IL-6 significantly higher in cases than controls
Original publication
Diet Quality Scores and Central Precocious Puberty Risk in Chinese Girls: A Case–Control Study. Clin Endocrinol (Oxf). Published 3 December 2024. doi:10.
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