A systematic review supporting the Endocrine Society clinical practice guidelines on central precocious puberty
An erratum to this article was published (J Clin Endocrinol Metab, 16 Oct 2026 ↗)
Pooled result · Adult height gain, girls with idiopathic CPPResult — go to the resultAdult height gain +2.7 cmAuthors' conclusion
This systematic review addresses various aspects of CPP evaluation and treatment of CPP and will support the development of the Endocrine Society guidelines.
Study context
- Population
- Children with central precocious puberty (CPP)32 citations included
- Comparison
- Gonadotropin-releasing hormone agonist (GnRHa) treatment vs no treatment; MRI in CPP without CNS symptoms
- Outcome
- Adult height gain, girls with idiopathic CPP
Methodological detailssupporting Endocrine Society clinical practice guidelines, 10 clinical questions, pairs of independent trained reviewers
- Supporting Endocrine Society clinical practice guidelines
- 10 clinical questions
- Pairs of independent trained reviewers
Pooled result
As reported in the abstract
Adult height gain
+2.7 cm
Original publication
A systematic review supporting the Endocrine Society clinical practice guidelines on central precocious puberty. J Clin Endocrinol Metab. Published 13 June 2026. doi:10.
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