Diabetes risk assessment in adult population without diabetes employing continuous glucose monitoring: A novel approach
Authors' conclusion
CGM provides highly useful information for predicting type 2 diabetes. In healthy individuals, exhibiting glucose levels at or above 130 mg/dL for over 10 % of the time over at least two monitoring days show a higher risk of developing type 2 diabetes.
Study context
- Population
- Adults without diabetes at baseline who completed continuous glucose monitoring (CGM); median age 46 (range 18–82)
- Participants
- 513 adults
- Exposure
- Individuals who developed diabetes vs those who did not
- Outcome
- Optimal cutoff for % of time glucose exceeds a threshold to predict diabetes onset
- Follow-up
- Median 10.8 years
Main finding
As reported in the abstract
Optimal CGM cutoff for predicting diabetes onset · median 10.8 years
- Most significant differences between those who developed diabetes and those who did not with a cutoff of ≥ 130 mg/dL for at least 10 % of monitoring time
Observational data: associations, not effects.
Further findings
Age · older with diabetes onset
P < 0.001
BMI · higher with diabetes onset
P < 0.001
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Diabetes risk assessment in adult population without diabetes employing continuous glucose monitoring: A novel approach. Diabetes Res Clin Pract. Published 29 May 2025. doi:10. 1016/ j. diabres. 2025. 112286
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