Automated Insulin Delivery in Elderly with Type 1 Diabetes: A Prespecified Analysis of the Extension Phase
Authors' conclusion
HCL was preferred over PLGS or SAP and remained effective in older adults with T1D.
Study context
- Population
- Adults ≥65 years with T1D who completed the AIDE T1D crossover trial; mean age 71 ± 4 years (range 65–86), mean T1D duration 42 ± 17 years (range 1–68)of 78 completers
- Participants
- 75 adults
- Comparison
- Self-selected pump mode
Methodological detailspump mode of participant's choice
- Pump mode of participant's choice
Primary result
As reported in the abstract
Pump mode selected · additional 3 months
Further findings
TIR 70-180 mg/dL among participants selecting hybrid closed loop (HCL) · RCT and extension phase
- TIR similar in the RCT and extension phase
- mean 75% ± 10%
Safety
Severe hypoglycaemia
- Severe hypoglycemic events reported
- 1
Original publication
Automated Insulin Delivery in Elderly with Type 1 Diabetes: A Prespecified Analysis of the Extension Phase. Diabetes Technol Ther. Published 11 March 2025. doi:10.
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