Pediatric endocrinology

Current Pubertal Development in Chinese Children and the Impact of Overnutrition, Lifestyle, and Perinatal Factors

J Clin Endocrinol MetabPublished Cross-sectional study

Authors' conclusion

Over the past decade, pubertal development is occurring earlier in Chinese children. While the cause is multifactorial, overweight and obesity are associated with earlier puberty onset. The currently used normative pubertal data of precocious puberty may not be applicable to diagnose precocious puberty.

Study context

Population
Chinese children and adolescents, nationally representative sample, 2017–2019; growth and pubertal staging by physical examination
Participants
231,575 children
Exposure
Boys vs Girls
  • Boysn = 123,232
  • Girlsn = 108,343
Outcome
Current status of sexual maturation
Methodological detailsnational, community-based health survey, multistage, stratified cluster random sampling, nationally representative sample
  • National
  • Community-based health survey
  • Multistage, stratified cluster random sampling
  • Nationally representative sample

Main finding

As reported in the abstract

Median age at pubertal milestones

Median age of Tanner 2 breast development (similar to 10 years previously)

9.65 years

Median age of menarche (similar to 10 years previously)

12.39 years

Median age of testicular volume ≥4 mL (male puberty earlier than 10 years previously)

10.65 years

Observational data: associations, not effects.

Secondary outcomes

Girls with breast development by age band

6.5-6.99 years old
3.3%
7.5-7.99 years old
5.8%

Boys with testicular volume ≥4 mL by age band

7.5-7.99 years
1.5%
8.5-8.99 years
3.5%

Weight status and earlier puberty

Obesity and overweight increased risk of earlier puberty vs normal weight in boys and girls

Original publication

Current Pubertal Development in Chinese Children and the Impact of Overnutrition, Lifestyle, and Perinatal Factors. J Clin Endocrinol Metab. Published 7 March 2023. doi:10.1210/clinem/dgad102

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