Trends in incidence of youth-onset type 1 and type 2 diabetes in the USA, 2002–18: results from the population-based SEARCH for Diabetes in Youth study
Authors' conclusion
The increasing incidence of type 1 and type 2 diabetes in children and young people in the USA will result in an expanding population of young adults at risk of developing early complications of diabetes whose health-care needs will exceed those of their peers. Findings regarding age and season of diagnosis will inform focused prevention efforts.
Study context
- Population
- Children and young people aged 0–19 years with physician-diagnosed type 1 or type 2 diabetes at five US centres, 2002–2018; non-military, non-institutionalised residents of study areas
- Participants
- 18,169 vs 5,293
- Exposure
- T1D vs T2D
- T1Dn = 18,169
- T2Dn = 5,293
- Outcome
- Incidence of T1D (per 100 000 aged <20 years) and T2D (per 100 000 aged 10 to <20 years) and its trends
- Follow-up
- 2002–2018
Methodological detailsfive US centres, generalised autoregressive moving average models
- Five US centres
- Generalised autoregressive moving average models
Main finding
As reported in the abstract
Annual incidence and annual linear trend · 2017-18
| Group | Value | Annual linear increase |
|---|---|---|
| T1D | 22.2 per 100 000 | 2.02% (95% CI 1.54-2.49) |
| T2D | 17.9 per 100 000 | 5.31% (4.46-6.17) |
Value
T1D22.2 per 100 000
T2D17.9 per 100 000
Annual linear increase
T1D2.02% (95% CI 1.54-2.49)
T2D5.31% (4.46-6.17)
Observational data: associations, not effects.
Further findings
Peak age at diagnosis
Increase by race or ethnicity
- Non-Hispanic Black and Hispanic children and young people had greater increases in incidence for both types
Season of diagnosis
- Season significant for T1D, January peak
- P = 0.0062
- Season significant for T2D, August peak
- P = 0.0006
Original publication
Trends in incidence of youth-onset type 1 and type 2 diabetes in the USA, 2002–18: results from the population-based SEARCH for Diabetes in Youth study. Lancet Diabetes Endocrinol. Published 28 February 2023. doi:10.
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