Correlation analysis of the abdominal visceral fat area with the structure and function of the heart and liver in obesity: a prospective magnetic resonance imaging study
Authors' conclusion
The high AVFA group had a larger LVM, GPWT and PATV, more obvious changes in LVER, impaired left ventricular diastolic function, an increased risk of heart disease, and more severe hepatic fat deposition and liver injury. Therefore, there is a correlation between the amount of visceral adipose tissue and subclinical cardiac changes and liver injury.
Study context
- Population
- Subjects with obesity
- Participants
- 69 subjects
- Exposure
- Abdominal visceral fat area (AVFA) ≥150 cm² vs 100 cm² ≤ AVFA <150 cm²
- Studyn = 41
- Controln = 28reference
- Outcome
- Cardiac and hepatic MRI indicators
Main finding
As reported in the abstract
Moderate positive correlation between AVFA and left ventricular eccentricity ratio (LVER), left ventricular mass (LVM), global peak wall thickness (GPWT), left ventricle global longitudinal strain (LVGLS) and hepatic proton density fat fraction (H-PDFF) (ρ)
0.39-0.59
P < 0.001
Observational data: associations, not effects.
Further findings
Clinical and laboratory indicators
- Higher incidences of T2D and insulin resistance and worse liver function indicators in study group
Original publication
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