Continuous glucose monitoring in patients with post‐bariatric hypoglycaemia reduces hypoglycaemia and glycaemic variability
Authors' conclusion
Real-time CGM data and alarms are associated with reductions in low sensor glucose, elevated sensor glucose, and glycaemic variability. This suggests CGM allows patients to detect hyperglycaemic peaks and imminent hypoglycaemia, allowing dietary modification and self-treatment to reduce hypoglycaemia. The use of CGM devices may improve safety in PBH, particularly for patients with hypoglycaemia unawareness.
Study context
- Population
- Individuals with post-bariatric hypoglycaemia (PBH); 12 wore Dexcom G4 for 28 days, 10 wore Dexcom G6 for 20 daysall in both phases
- Participants
- 22 individuals
- Comparison
- Unmasked vs masked continuous glucose monitoring (CGM)
- Outcome
- Hypoglycaemia (% time in hypoglycaemia)
Methodological detailsopen-label, nonrandomized, sequential assignment
- Open-label
- Nonrandomized
- Sequential assignment
Main finding
As reported in the abstract
- Similar trends overnight
- Unmasked vs Masked: P = 0.03
- Unmasked vs Masked: P = 0.04
Further findings
% time 3.9–10 mM/L (70-180 mg/dL) · 24 h
P = 0.004
% time in normoglycaemia, daytime · day
P = 0.005
% time in hyperglycaemia (>10 mM/L, or 180 mg/dL), daytime · day
P = 0.02
Mean amplitude of glycaemic excursion · 24 h
P = 0.04
Original publication
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