Comparison of Glycemia Risk Index with Time in Range for Assessing Glycemic Quality
Authors' conclusion
The GRI is a useful tool for assessing glycemic quality in clinical practice and reflects hypoglycemia better than does TIR.
Study context
- Population
- Insulin-treated adults with diabetes; ninety-day continuous glucose monitoring (CGM) tracings524 CGM tracings
- Participants
- 194 adults
- Exposure
- Glycemia risk index (GRI) vs time in range (TIR) for assessing glycemic quality
- Outcome
- Correlation of GRI with CGM metrics
Main finding
As reported in the abstract
- Correlation of GRI with TIR
- r = −0.974
- Correlation of GRI with CV
- r = 0.683
- Within each TIR group (50% to <60%, 60% to <70%, 70% to <80%, ≥80%), GRI increased as time below range (TBR)<70 mg/dL increased
- P < 0.001 for all TIR groups
Observational data: associations, not effects.
Further findings
Longitudinal: improvement in TBR<70 mg/dL
- GRI improved significantly
- P = 0.003
- TIR did not improve
- P = 0.704
Longitudinal: improvement in time above range (TAR)>180 mg/dL
- Both GRI and TIR improved
- P < 0.001 for both
GRI grid
- Longitudinal change was easily identifiable on a GRI grid
Original publication
Comparison of Glycemia Risk Index with Time in Range for Assessing Glycemic Quality. Diabetes Technol Ther. Published 25 October 2023. doi:10.
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