Osteoporosis, bone & mineral

Comparison of DXA-based versus CT-based indices to predict prevalent fracture history in men with spinal cord injury

Osteoporos IntPublished Diagnostic accuracy study

Authors' conclusion

CT imaging may have clinical utility to improve fracture risk prediction in adults with SCI.

Study context

Population
Men with known spinal cord injurymen with SCI
Participants
36 men
Comparison
DXA-based vs CT-based indices to identify prevalent fracture history
Outcome
Discrimination (AUC) of prevalent fracture history
Methodological detailsage-adjusted AUC models
  • Age-adjusted AUC models

Performance

As reported in the abstract

Discrimination of prevalent fracture history (AUC)
  • CT-based indices outperformed DXA-based indices at all sites
  • Highest AUC: trabecular BMD at the proximal tibial epiphysis

Original publication

Comparison of DXA-based versus CT-based indices to predict prevalent fracture history in men with spinal cord injury. Osteoporos Int. Published 23 November 2022. doi:10.1007/s00198-022-06575-9

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