Comparative longitudinal assessment of bone mineral density measured with radiofrequency echographic multi-spectrometry (REMS) and dual X-ray absorptiometry (DXA) in a cohort of peritoneal dialysis patients
Authors' conclusion
DXA detected a significant decline in BMD at cortical sites, whereas REMS did not, and the correlation of the annualized changes between the two methods in assessing changes over time was poor.
Study context
- Population
- Peritoneal dialysis patients undergoing two separate DXA and REMS evaluations
- Participants
- 20 patients
- Exposure
- REMS vs DXA for longitudinal bone mineral density (BMD) assessment
- Outcome
- Longitudinal BMD changes assessed by DXA and REMS
- Follow-up
- Median 19.8 months
Methodological detailslongitudinal, comparative measurement study
- Longitudinal
- Comparative measurement study
Main finding
As reported in the abstract
BMD change at femoral neck
| Group | Value | P |
|---|---|---|
| DXA | −3.2% | p = 0.039 |
DXA
Value−3.2%
Pp = 0.039
- DXA vs REMS: P = 0.229 — similar trajectories
- DXA vs REMS: P = 0.806 — similar trajectories
Observational data: associations, not effects.
Further findings
Correlation of annualized BMD changes between REMS and DXA
- Femoral neck (FN): r2 = 0.001
- P = 0.905
- Lumbar spine (LS): r2 = 0.001
- P = 0.928
- No correlation
Original publication
Comparative longitudinal assessment of bone mineral density measured with radiofrequency echographic multi-spectrometry (REMS) and dual X-ray absorptiometry (DXA) in a cohort of peritoneal dialysis patients. Osteoporos Int. Published 9 April 2026. doi:10. 1007/ s00198-026-07959-x
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