Gestational diabetes & diabetes in pregnancy
Clinical readiness of first-trimester gestational diabetes prediction: From risk score to care pathway
Authors' conclusion
First-trimester scores should not replace recommended diagnostic testing. Clinical adoption requires local validation, a prespecified beneficial action, evaluation of costs and harms, and comparative trials measuring maternal and neonatal outcomes.
Study context
- Outcome
- Routine clinical and glycemic predictors of GDM
Methodological detailsnon-systematic searches
- Non-systematic searches
Main finding
As reported in the abstract
- Routine clinical and glycemic predictors are feasible, but transportability, calibration, and strategy-level benefit are not established consistently
Further findings
RESPECT 2 implementation
- RESPECT 2 demonstrated implementation feasibility
Gestational diabetes mellitus (GDM) in a trial of nutrition support in model-selected women
- Model-selected women in the trial
- 519
- Nutrition support in model-selected women did not significantly reduce GDM
TOBOGM
- TOBOGM investigated treatment after early biochemical diagnosis, not care guided by a risk score
Direct trials of the complete prediction-guided strategy
- Direct trials of the complete prediction-guided strategy remain limited
Original publication
Clinical readiness of first-trimester gestational diabetes prediction: From risk score to care pathway. Diabetes Res Clin Pract. Published 13 November 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →