Clinical and psychological phenotypes of type 1 diabetes and disordered eating derived from a case vignette series: T1DE phenotypes
Study context
- Population
- People with T1D and disordered eating from baseline assessments of STEADY and the London-T1DE pilot service at King's College Hospital; 94.3% women, age 34.5 ± 10.6 years, diabetes duration 18.4 ± 12.5 years, HbA1c 84.8 ± 32.9 mmol/mol (10.2 ± 3.0%)94.3% women
- Participants
- 70 people
- Comparison
- Insulin-omission T1DE vs Restrict T1DE vs Binge T1DE
- Insulin-omission (diabulimia) T1DEn = 28
- Restrict T1DEn = 17
- Binge T1DEn = 25
- Outcome
- T1DE phenotypes
Methodological detailsdescriptive phenotyping study, anonymised case vignettes, iterative phenotype development, clinical severity grading framework
- Descriptive phenotyping study
- Anonymised case vignettes
- Iterative phenotype development
- Clinical severity grading framework
Main finding
As reported in the abstract
Further findings
Clinical severity grading
- Low clinical risk
- 19 (27.1%)
- Moderate clinical risk
- 23 (32.9%)
- Severe clinical risk
- 28 (40.0%)
Formal eating disorder diagnosis (ICD-10/DSM-5)
- Other specified feeding or eating disorder
- 34
- Bulimia nervosa
- 27
- Anorexia nervosa
- 6
- Binge eating disorder
- 2
- All but one fulfilled criteria for a formal eating disorder diagnosis
Psychiatric comorbidity
- Mood disorder
- Over 50%
- Anxiety disorder
- 44.3%
- Trauma-related disorder
- 20.0%
Original publication
Clinical and psychological phenotypes of type 1 diabetes and disordered eating derived from a case vignette series: T1DE phenotypes. Diabetologia. Published 26 May 2026. doi:10. 1007/ s00125-026-06756-9
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