Type 1 diabetes

Clinical and psychological phenotypes of type 1 diabetes and disordered eating derived from a case vignette series: T1DE phenotypes

DiabetologiaPublished Case vignette series

Study context

Population
People with T1D and disordered eating from baseline assessments of STEADY and the London-T1DE pilot service at King's College Hospital; 94.3% women, age 34.5 ± 10.6 years, diabetes duration 18.4 ± 12.5 years, HbA1c 84.8 ± 32.9 mmol/mol (10.2 ± 3.0%)94.3% women
Participants
70 people
Comparison
Insulin-omission T1DE vs Restrict T1DE vs Binge T1DE
  • Insulin-omission (diabulimia) T1DEn = 28
  • Restrict T1DEn = 17
  • Binge T1DEn = 25
Outcome
T1DE phenotypes
Methodological detailsdescriptive phenotyping study, anonymised case vignettes, iterative phenotype development, clinical severity grading framework
  • Descriptive phenotyping study
  • Anonymised case vignettes
  • Iterative phenotype development
  • Clinical severity grading framework

Main finding

As reported in the abstract

Further findings

Clinical severity grading

Low clinical risk
19 (27.1%)
Moderate clinical risk
23 (32.9%)
Severe clinical risk
28 (40.0%)

Formal eating disorder diagnosis (ICD-10/DSM-5)

Other specified feeding or eating disorder
34
Bulimia nervosa
27
Anorexia nervosa
6
Binge eating disorder
2
All but one fulfilled criteria for a formal eating disorder diagnosis

Psychiatric comorbidity

Mood disorder
Over 50%
Anxiety disorder
44.3%
Trauma-related disorder
20.0%

Original publication

Clinical and psychological phenotypes of type 1 diabetes and disordered eating derived from a case vignette series: T1DE phenotypes. Diabetologia. Published 26 May 2026. doi:10.1007/s00125-026-06756-9

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