Impact of automated insulin delivery on subjective and objective sleep in children and young adults with very high HbA1c : Sleep outcomes from the CO ‐ PILOT randomised controlled trial
Authors' conclusion
Although AID improved some subjective sleep aspects, sleep efficiency reduced and WASO increased. The relationship between glycaemia and sleep remains unclear, suggesting that effective sleep improvement in young people with T1D may require multifactorial approaches extending beyond improving glycaemia.
Study context
- Population
- Young people aged 7–25 years with T1D and suboptimal glycaemia (HbA1c ≥ 69 mmol/mol)all completed
- Participants
- 80 people
- Comparison
- Automated insulin delivery (AID) vs usual care
- Primary endpoint
- Sleep (secondary outcome of the trial): subjective (questionnaires) and objective (accelerometry)
- Follow-up
- 13 weeks
Primary result
As reported in the abstract
Sleep outcomes:
- Subjective: questionnaires
- Objective: accelerometry
Intervention vs ControlsMD (95% CI)P value
Sleep-related impairment; improved more with intervention
−4.7(−8.7 to −0.8)
P = 0.02Sleep efficiency; decline with intervention
−4.2(−8.0 to −0.3)
P = 0.03Intervention vs ControlsMD, minutes (95% CI)P value
WASO; more minutes awake with intervention
21(1–41)
P = 0.04Secondary outcomes
| Outcome | MD (mmol/mol) (95% CI) | P value | |
|---|---|---|---|
| HbA1c · 13 weeksInterventionvs ControlsImprovement with intervention | −34 (−43 to −25) | P < 0.001 | |
| −60−40−20020Difference, mmol/mol (linear scale) |
Original publication
Impact of automated insulin delivery on subjective and objective sleep in children and young adults with very high HbA1c : Sleep outcomes from the CO ‐ PILOT randomised controlled trial. Diabet Med. Published 18 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →