Gestational diabetes & diabetes in pregnancy
Childhood adversity and the risk of gestational diabetes: A population‐based cohort study of nulliparous pregnant women
Authors' conclusion
Experiencing childhood adversity to any extent is associated with a higher risk of GDM. Interventions aimed at preventing childhood adversity may have a positive effect in reducing GDM burden and the associated health risks.
Study context
- Population
- Nulliparous women giving birth for the first time, 2004–2018, Danish nationwide registers
- Participants
- 208,207 women
- Exposure
- Childhood adversity groups vs low adversity
- Outcome
- GDM
Methodological detailsnationwide register data
- Nationwide register data
Main finding
As reported in the abstract
GDM risk (direct effect)
Each group vs lowAbsolute difference, % (95% CI)
Early life material deprivation
0.64(0.44–0.84)
Persistent deprivation
0.63(0.41–0.86)
Loss or threat of loss
0.73(0.42–1.05)
High adversity
0.80(0.32–1.27)
- Gestational diabetes mellitus (GDM) diagnosed in study population
- 5375 (2.6% absolute risk)
Observational data: associations, not effects.
Further findings
Indirect effect of maternal age
- Attenuation of total effect of childhood adversity on GDM (absolute difference)
- 0.25%-0.46%
Original publication
Childhood adversity and the risk of gestational diabetes: A population‐based cohort study of nulliparous pregnant women. Diabet Med. Published 31 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →