Characterizing echocardiographic abnormalities and their associated factors in patients with type 1 diabetes: a cross-sectional study
Authors' conclusion
This study revealed a high prevalence of echocardiographic abnormalities in patients with type 1 diabetes, linked to aging, obesity, smoking, hypertension, islet function, thyroid function, renal function, and cardiovascular comorbidities. Further studies are needed to validate these findings.
Study context
- Population
- Patients with T1D
- Participants
- 362 patients
- Outcome
- Prevalence of echocardiographic abnormalities (structural abnormalities or diastolic dysfunction) and associated factors
Main finding
As reported in the abstract
Prevalence of echocardiographic abnormalities
Echocardiographic abnormalities
32.60%
Cardiac structural abnormalities
19.61%
Ventricular diastolic dysfunction
21.27%
Observational data: associations, not effects.
Further findings
Factors associated with echocardiographic abnormalities (modified Poisson regression)
- Older age, prevalence ratio (PR)
- 1.04 (95% CI 1.03 to 1.05)
- Male sex, PR
- 1.60 (95% CI 1.04 to 2.47)
- Smoking history, PR
- 1.85 (95% CI 1.21 to 2.83)
- Older onset age, PR
- 0.93 (95% CI 0.88 to 0.98)
- Higher SBP, PR
- 1.014 (95% CI 1.007 to 1.020)
- WHR in female, PR
- 1.022 (95% CI 1.005 to 1.039)
- WHtR in female, PR
- 1.028 (95% CI 1.004 to 1.053)
- Higher FCP, PR
- 1.23 (95% CI 1.08 to 1.40)
- Higher 2 h-CP, PR
- 1.08 (95% CI 1.02 to 1.14)
- Higher ICA titer, PR
- 0.97 (95% CI 0.95 to 0.99)
- Elevated FT4, PR
- 1.03 (95% CI 1.01 to 1.05)
- Elevated FT3, PR
- 1.11 (95% CI 1.02 to 1.21)
- Elevated UACR, PR
- 1.0002 (95% CI 1.00003 to 1.0004)
- Hypertension, PR
- 1.37 (95% CI 1.04 to 1.80)
Original publication
Characterizing echocardiographic abnormalities and their associated factors in patients with type 1 diabetes: a cross-sectional study. Cardiovasc Diabetol. Published 30 September 2025. doi:10.
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