Beyond overweight, visceral adiposity is associated with estimation of cardiovascular risk in patients living with type 1 diabetes: findings from the SFDT1 cohort
Authors' conclusion
In PWT1D in condition of primary CV prevention, visceral adiposity, assessed by WHtR, is a more robust marker of estimated 10-year CV risk than overweight/obesity status in both men and women.
Study context
- Population
- People living with T1D in primary cardiovascular (CV) prevention, SFDT1 cohort
- Participants
- 1,482 people
- Exposure
- Body mass index (BMI) ≥25 vs normal BMI; Waist-to-height ratio (WHtR) ≥0.5 vs <0.5
- Outcome
- High estimated 10-year CV risk (> 20%, Steno Type 1 Risk Engine)
- Follow-up
- 10-year
Methodological detailsSFDT1 cohort
- SFDT1 cohort
Main finding
As reported in the abstract
High estimated 10-year CV risk
- BMI associated with high CV risk in men
- P = 0.001
- BMI non-significant trend with high CV risk in women
- P = 0.053
- WHtR associated with high CV risk in men
- P < 0.001
- WHtR associated with high CV risk in women
- P = 0.046
Observational data: associations, not effects.
Further findings
| Outcome | Overweight/obesity | Normal BMI |
|---|---|---|
| BMI distribution | 50.1% | 49.9% |
ROC thresholds associated with high CV risk
- BMI threshold, men
- 24.9 kg/m²
- WHtR threshold, men and women
- 0.5
Original publication
Beyond overweight, visceral adiposity is associated with estimation of cardiovascular risk in patients living with type 1 diabetes: findings from the SFDT1 cohort. Cardiovasc Diabetol. Published 14 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →