Waist-to-Height Ratio Is Associated With the Risk of Coronary Artery Disease in Type 1 Diabetes: A 19-Year Cohort Study
Main finding · CAD per 0.1-unit WHtR increaseResult — go to the resultHazard ratio 1.21 95% CI 1.06–1.38Authors' conclusion
In conclusion, WHtR is associated with increased CAD risk in type 1 diabetes, particularly among those without albuminuria.
Study context
- Population
- Individuals with T1D without prior coronary artery disease (CAD), Finnish Diabetic Nephropathy Study
- Participants
- 4,349 individuals
- Exposure
- Central obesity vs no central obesity
- Outcome
- CAD: acute MI, coronary revascularizations and CAD-related death
- Follow-up
- median 19-year follow-up
Methodological detailsmultivariable Cox regression adjusted for baseline covariates
- Multivariable Cox regression adjusted for baseline covariates
Main finding
CAD per 0.1-unit WHtR increase
Hazard ratio
1.21
95% CI 1.06–1.38
P = 0.006
Per 0.1-unit WHtR increase
HR 1.21 (95% CI 1.06–1.38); P = 0.006
Per 0.1-unit WHtR increase, as printed
As reported in the abstract
- CAD events overall
- 664 (15.3%)
Observational data: associations, not effects.
Further findings
Cumulative CAD incidence · 10 years
Cumulative CAD incidence · 20 years
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| CAD per 0.1-unit WHtR increase, subgroup without albuminuriaWithout albuminuria | 1.26 (1.02–1.56) | P = 0.03 | |
| 0.512Hazard ratio (log scale) |
Original publication
Waist-to-Height Ratio Is Associated With the Risk of Coronary Artery Disease in Type 1 Diabetes: A 19-Year Cohort Study. Diabetes Care. Published 14 April 2026. doi:10.
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