Gestational diabetes & diabetes in pregnancy
Beyond Gestational Diabetes: Maternal and Offspring Health and Lifestyle 3 Years Postnatally in a Secondary Analysis of the UPBEAT Trial Cohort
Authors' conclusion
Women with GDM demonstrated reduced gestational weight gain, and despite a higher BMI than women without GDM in early pregnancy, this difference was not evident at 3 years postpartum. However, while maternal and offspring dietary behaviours were comparable between groups, exposed offspring were at increased risk of overweight/obesity at 3 years of age.
Study context
- Population
- Women with obesity recruited to the UPBEAT RCT with 3-year postnatal follow-up, and their offspring
- Participants
- 441 women
- Comparison
- GDM vs no GDM
- Primary endpoint
- Maternal and child health (anthropometry, diet) 3 years postpartum
- Follow-up
- 3 years postpartum
Methodological details3-year postnatal follow-up, linear/logistic regression adjusted for confounders
- 3-year postnatal follow-up
- Linear/logistic regression adjusted for confounders
Primary result
As reported in the abstract
Maternal BMI
GDM-exposed offspring more likely overweight/obese at 3 years (IOTF standards)
OR 2.32; 95% CI 1.38, 3.91
Further findings
| Outcome | GDM | P value |
|---|---|---|
| Maternal BMI at ≈16 weeks' gestationGDM vs No GDM · higher with GDM | median 35.6 kg/m² | P = 0.049 |
| Energy intake at ≈16 weeks' gestationGDM vs No GDM · higher with GDM | 1738.2 kcal/day | P = 0.005 |
| Gestational weight gainGDM vs No GDM · lower with GDM | 4.5 kg | P < 0.001 |
| Infant birthweight centile · birthGDM vs No GDM · higher with GDM | 55.4 th centile | P = 0.008 |
- Maternal BMI at ≈16 weeks' gestation: No GDM median 34.2 kg/m²
- Energy intake at ≈16 weeks' gestation: No GDM 1551.6 kcal/day
- Gestational weight gain: No GDM 6.6 kg
- Infant birthweight centile: No GDM 45.9 th centile
Original publication
Beyond Gestational Diabetes: Maternal and Offspring Health and Lifestyle 3 Years Postnatally in a Secondary Analysis of the UPBEAT Trial Cohort. Pediatr Obes. Published 10 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →