Association of temporal change in body mass index with sudden cardiac arrest in diabetes mellitus
Authors' conclusion
In diabetes mellitus, sustained underweight as well as decrease in body weight during 4-year follow-up imposes substantial risk on SCA. Recovery from underweight over time had relatively lower, but yet increased risk of SCA. Both underweight and dynamic decrease in BMI can be associated with increased risk of SCA.
Study context
- Population
- Patients with DM with health examination in 2009–2012 and prior examination 4 years earlier (2005–2008), Korean National Health Insurance Service database
- Participants
- 1,355,746 patients
- Exposure
- Body mass index (BMI) status and its 4-year change: sustained underweight, previous underweight and newly developed underweight vs sustained non-underweight
- Outcome
- Occurrence of sudden cardiac arrest (SCA)
Methodological detailsnationwide database (Korean National Health Insurance Service)
- Nationwide database (Korean National Health Insurance Service)
Main finding
As reported in the abstract
SCA
Each group vs sustained non-underweightAdjusted hazard ratio (95% CI)
Sustained underweight
2.60(2.25–3.00)
Newly developed underweight
2.42(2.15–2.74)
Previous underweight
2.12(1.77–2.53)
- Sudden cardiac arrest (SCA) cases
- 12,554
Observational data: associations, not effects.
Original publication
Association of temporal change in body mass index with sudden cardiac arrest in diabetes mellitus. Cardiovasc Diabetol. Published 28 January 2024. doi:10. 1186/ s12933-024-02130-4
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