Association of polycystic ovary syndrome with cardiovascular disease among female hospitalizations in the United States
Authors' conclusion
Polycystic ovary syndrome is associated with CVD events and the association is mediated by obesity and metabolic syndrome conditions, particularly among hospitalized women aged ≤40 years in the United States.
Study context
- Population
- Hospitalizations of women aged 15–65 years, National Inpatient Sample, US, 2017
- Exposure
- Polycystic ovary syndrome (PCOS) vs no PCOS
- PCOSn = 13,896
- Outcome
- CVD outcomes among hospitalized women aged ≤40 years
Methodological detailsNational Inpatient Sample database, 2017, sampling-weighted logistic regression
- National Inpatient Sample database, 2017
- Sampling-weighted logistic regression
Main finding
As reported in the abstract
Each group vs no PCOSEstimate (95% CI)P value
PCOS
aOR, composite CVD 1.73(1.55–1.93)
P < 0.001PCOS
aOR, MACE 1.31(1.12–1.53)
P < 0.001PCOS
aOR, CHD 1.65(1.35–2.01)
P < 0.001PCOS
aOR, stroke/CVA 1.46(1.08–1.98)
P = 0.014PCOS
aOR, HF 1.30(1.07–1.57)
P = 0.007PCOS
aOR, AF/arrhythmia 2.20(1.88–2.57)
P < 0.001PCOS
aOR, PHD 1.58(1.23–2.03)
P < 0.001Observational data: associations, not effects.
Original publication
Association of polycystic ovary syndrome with cardiovascular disease among female hospitalizations in the United States. Eur J Endocrinol. Published 12 June 2023. doi:10.
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