Rising Incidence, Health Resource Utilization, and Costs of Polycystic Ovary Syndrome in the United Kingdom
Authors' conclusion
The incidence of PCOS has risen significantly. Health resource utilization and costs of PCOS are significantly greater than controls.
Study context
- Population
- Patients with Polycystic Ovary Syndrome (PCOS) in the UK, Clinical Practice Research Datalink Aurum and Hospital Episode Statistics, 2004–2020matched 1:1
- Exposure
- PCOS vs matched controls
- Outcome
- PCOS incidence and point prevalence
- Follow-up
- 2004-2020
Methodological detailsmatched 1:1 by age, BMI and primary care practice, Clinical Practice Research Datalink Aurum and Hospital Episode Statistics databases, Primary care contacts assigned an average cost; prescriptions a net ingredient cost; inpatient and outpatient care costed to the national tariff via healthcare resource groups
- Matched 1:1 by age, BMI and primary care practice
- Clinical Practice Research Datalink Aurum and Hospital Episode Statistics databases
- Primary care contacts assigned an average cost; prescriptions a net ingredient cost; inpatient and outpatient care costed to the national tariff via healthcare resource groups
Main finding
As reported in the abstract
2004-2020
- PCOS incidence, 2004
- 1.22 per 1000 person years
- PCOS incidence, 2012
- 1.77 per 1000 person years
- PCOS incidence, 2019
- 2.20 per 1000 person years
- Point prevalence, 2004
- 1.02%
- Point prevalence, 2012
- 2.2%
- Point prevalence, 2020
- 3.5%
Observational data: associations, not effects.
Further findings
Inpatient contacts per person year (ppy)
P < 0.001
Outpatient contacts ppy
P < 0.001
Primary care contacts ppy
P < 0.001
- Mean healthcare costs ppy: inpatients
- P < 0.001
- Mean healthcare costs ppy: outpatients
- P < 0.001
- Mean healthcare costs ppy: primary care prescriptions
- P < 0.001
Point prevalence of PCOS · 2004, 2012, 2020
- Point prevalence 2004
- 1.02%
- Point prevalence 2012
- 2.2%
- Point prevalence 2020
- 3.5%
- Prevalence highest in Asians
Total healthcare contacts and total costs ppy
- Total healthcare contacts ppy
- P < 0.001
- Total associated costs
- P < 0.001
- Health resource utilization and costs of PCOS significantly greater than controls
Original publication
Rising Incidence, Health Resource Utilization, and Costs of Polycystic Ovary Syndrome in the United Kingdom. J Clin Endocrinol Metab. Published 25 July 2024. doi:10.
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