Gestational diabetes & diabetes in pregnancy
Association of Continuous Glucose Monitoring Metrics With Pregnancy Outcomes in Patients With Preexisting Diabetes
Authors' conclusion
Nearly all CGM metrics were associated with adverse neonatal morbidity and mortality and may aid management of preexisting diabetes in pregnancy. Our findings support the American Diabetes Association recommendation of 70% TIR.
Study context
- Population
- Pregnant patients with T1D or T2D using real-time continuous glucose monitoring (CGM), delivered at a U.S. tertiary center (2018–2021); multiple gestations, fetal anomalies and early pregnancy loss excluded68 (58.1%) T1D
- Participants
- 117 patients
- Exposure
- Association of CGM metrics with perinatal outcomes
- Outcome
- Composite of:
- Fetal or neonatal mortality
- Large or small for gestational age at birth
- Neonatal ICU admission
- Hypoglycemia
- Shoulder dystocia or birth trauma
- Hyperbilirubinemia
Methodological detailssingle tertiary centre, Used CGM before pregnancy: 16 (13.7%)
- Single tertiary centre
- Used CGM before pregnancy: 16 (13.7%)
Main finding
As reported in the abstract
Composite neonatal outcome
Developed the composite neonatal outcome
98 patients
83.8%
OR of neonatal morbidity per 5 percentage-point increase in time in range (TIR)
0.72
95% CI 0.58–0.89
Statistically optimal TIR
66-71%
Observational data: associations, not effects.
Original publication
Association of Continuous Glucose Monitoring Metrics With Pregnancy Outcomes in Patients With Preexisting Diabetes. Diabetes Care. Published 2 October 2023. doi:10.
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