Gestational diabetes & diabetes in pregnancy
Continuous Glucose Monitoring Metrics and Perinatal Outcomes in Pregnant Women with Type 2 Diabetes
Authors' conclusion
In women with T2D, poorer CGM-assessed glycemic control was associated with perinatal events from early pregnancy.
Study context
- Population
- Pregnant women with T2D who delivered between January 2020 and August 2025 and used continuous glucose monitoring (CGM) for ≥7 days; mean age 34 ± 6 years, BMI 33 ± 7 kg/m², HbA1c 7.4% ± 1.7%; 24 (30%) diagnosed during pregnancy
- Participants
- 80 women
- Exposure
- CGM metrics in women with vs without perinatal events
- Eventsn = 53
- Outcome
- Composite of:
- Preterm birth (<37 weeks)
- Large-for-gestational-age infant
- Neonatal hypoglycemia
- Shoulder dystocia
- Neonatal ICU admission
- Hyperbilirubinemia
- Perinatal mortality
Methodological detailssingle-center
- Single-center
Main finding
As reported in the abstract
With events
66%
53
Mean difference (TIR63-140), percentage points (95% CI)
With eventsvs Without events
−8.1(−13.2 to −3.0)
Adjusted odds ratio (95% CI)
Each 10-point decrease in TIR63-140
1.82(1.19–3.00)
Each 10-point decrease in TIR63-140, as printed
- With events vs Without events
- mean difference (mean glucose) +11 mg/dL (95% CI +5 to +16)
Observational data: associations, not effects.
Further findings
Glycemic target achievement (time in range (TIR63-140))
- Mean TIR63-140
- 72% ± 13%
- Achieved TIR63-140 ≥70%
- 50 (63%)
- Achieved TIR63-140 ≥80%
- 19 (24%)
- Achieved TIR63-140 ≥90% target
- 5 (6%)
- Median (IQR) CGM use, days
- 118 (69-187)
Original publication
Continuous Glucose Monitoring Metrics and Perinatal Outcomes in Pregnant Women with Type 2 Diabetes. Diabetes Technol Ther. Published 2 July 2026. doi:10. 1177/ 15209156261466873
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