Association of a lifestyle score with cardiometabolic markers among individuals with diabetes: a cross-sectional study
Authors' conclusion
Adherence to each additional healthy lifestyle factor was beneficially associated with cardiovascular risk markers, indicators of fatty liver disease and adipose tissue mass. Strongest associations were observed for adherence to all healthy lifestyle factors in combination.
Study context
- Population
- Adults with new-onset diabetes from the German Diabetes Study: T1D (median age 35 years; median body mass index (BMI) 24 kg/m²) and T2D (median age 53 years; median BMI 31 kg/m²)196 T1D, 272 T2D
- Exposure
- High vs low adherence to a healthy lifestyle score
- Outcome
- Cardiometabolic markers, high vs low lifestyle score adherence (β)
Methodological detailsScore 0–5: healthy diet, moderate alcohol, recreational activity, non-smoking, non-obese BMI; multivariable linear and non-linear regression
- Score 0–5: healthy diet, moderate alcohol, recreational activity, non-smoking, non-obese BMI; multivariable linear and non-linear regression
Main finding
As reported in the abstract
- High adherence
- β TG −49.1 mg/dL (95% CI −76.7 to −21.4)
- High adherence
- β LDL-C −16.7 mg/dL (95% CI −31.3 to −2.0)
- High adherence
- β HDL-C 13.5 mg/dL (95% CI 7.6–19.4)
- High adherence
- β HbA1c −0.5% (95% CI −0.8% to −0.1%)
- High adherence
- β high-sensitivity C reactive protein −0.4 mg/dL (95% CI −0.6 to −0.2)
- High adherence
- β hepatic fat content −8.3% (95% CI −11.9% to −4.7%)
- High adherence
- β visceral adipose tissue mass −1.8 dm³ (95% CI −2.9 to −0.7)
Observational data: associations, not effects.
Further findings
Distribution of adherence to favorable lifestyle factors
- None or one
- 8.1%
- Two
- 17.7%
- Three
- 29.7%
- Four
- 26.7%
- All five
- 17.7%
Dose-response
- Every additional healthy lifestyle factor associated with more beneficial risk profiles
Original publication
Association of a lifestyle score with cardiometabolic markers among individuals with diabetes: a cross-sectional study. BMJ Open Diabetes Res Care. Published 11 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →