Lipids & metabolic liver disease
Association between the triglyceride glucose index and in-hospital and 1-year mortality in patients with chronic kidney disease and coronary artery disease in the intensive care unit
Authors' conclusion
This study shows that TyG is a predictor of one-year mortality and in-hospital mortality in ICU patients with CAD and CKD and inform the development of new interventions to improve outcomes. In the high-risk group, TyG might be a valuable tool for risk categorization and management. Further research is required to confirm these results and identify the mechanisms behind the link between TyG and mortality in CAD and CKD patients.
Study context
- Population
- Intensive care unit (ICU) patients with chronic kidney disease (CKD) and coronary artery disease, MIMIC-IV database (2008–2019)
- Participants
- 639 patients
- Outcome
- In-hospital and 1-year mortality
Methodological detailsMIMIC-IV database, Boruta feature selection, logistic regression, Cox regression and restricted cubic spline analyses
- MIMIC-IV database
- Boruta feature selection
- Logistic regression, Cox regression and restricted cubic spline analyses
Main finding
As reported in the abstract
Median TyG index
9.1
8.6,9.5
Observational data: associations, not effects.
Original publication
Association between the triglyceride glucose index and in-hospital and 1-year mortality in patients with chronic kidney disease and coronary artery disease in the intensive care unit. Cardiovasc Diabetol. Published 13 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →