Lipids & metabolic liver disease
Association between triglyceride-glucose index and all-cause mortality in critically ill patients with ischemic stroke: analysis of the MIMIC-IV database
Authors' conclusion
The TyG index has a significant association with hospital and ICU all-cause death in critically ill patients with IS. This finding demonstrates that the TyG index might be useful in identifying patients with IS at high risk of all-cause death.
Study context
- Population
- Critically ill patients with severe ischemic stroke requiring intensive care unit (ICU) admission, MIMIC-IV database; 55.8% male
- Participants
- 733 patients
- Exposure
- Elevated vs lower triglyceride-glucose (TyG) index
- Outcome
- In-hospital mortality and ICU mortality
Methodological detailsMIMIC-IV database, TyG index quartiles, Cox proportional hazards regression, restricted cubic splines
- MIMIC-IV database
- TyG index quartiles
- Cox proportional hazards regression
- Restricted cubic splines
Main finding
As reported in the abstract
All-cause mortality by TyG index
Hospital mortality, overall cohort
19.0%
ICU mortality, overall cohort
14.9%
Elevated TyG index and hospital mortality: aHR
1.371
95% CI 1.053–1.784P = 0.013
Elevated TyG index and ICU mortality: aHR
1.653
95% CI 1.244–2.197P = 0.001
Observational data: associations, not effects.
Original publication
Association between triglyceride-glucose index and all-cause mortality in critically ill patients with ischemic stroke: analysis of the MIMIC-IV database. Cardiovasc Diabetol. Published 13 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →