Association between sex, age, temporal trends, and glycemic control of 221,769 adults with type 2 diabetes in a multi-ethnic middle-income Asian country
Authors' conclusion
A more aggressive approach to type 2 diabetes management is needed for both sexes, targeting especially the younger age groups, to improve glycemic control and reduce diabetes burden.
Study context
- Population
- Adult Malaysians with T2D, National Diabetes Registry (2011–2020); Malays 61.8 %, females 59.3 %, aged 50–69 years 63.5 %
- Participants
- 221,769 participants
- Exposure
- Females vs males, by age and over time
- Outcome
- HbA1c levels (5th, 50th, 95th percentile) and odds of good control (HbA1c < 7 %)
Methodological detailsnational registry, multi-ethnic
- National registry
- Multi-ethnic
Main finding
As reported in the abstract
Good control (HbA1c < 7 %)
Adjusted odds, at 30 years
0.90
95 % CI 0.81–0.99
Females
Adjusted odds, at 50 years
0.93
95 % CI 0.90–0.97
Females
Adjusted odds, at 70 years
1.12
95 % CI 1.08–1.16
Females
- Females had increasingly better control than men with increasing age
- P for heterogeneity < 0.001
Observational data: associations, not effects.
Further findings
HbA1c
Temporal trend in glycemic control · 2011 to 2020
- Glycemic control improved from 2011 to 2020 for both females and males above 40
Original publication
Association between sex, age, temporal trends, and glycemic control of 221,769 adults with type 2 diabetes in a multi-ethnic middle-income Asian country. Diabetes Res Clin Pract. Published 30 December 2024. doi:10.
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