Association between RDW-SD and prognosis across glycemic status in patients with dilated cardiomyopathy
Authors' conclusion
RDW-SD was independently associated with the outcome in patients with DCM with pre-DM and DM, suggesting potential individualized therapeutic targets for this subset of patients with DCM.
Study context
- Population
- Patients hospitalized for non-ischemic dilated cardiomyopathy (DCM), Fuwai Hospital, 2006–2021; median age 48 years, 23.5% women
- Participants
- 1,102 patients
- Exposure
- RDW-SD per SD increase, overall and by glycemic status
- Outcome
- All-cause mortality and heart transplantation
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Primary outcome per SD increase in RDW-SD, by glycemic status
Adjusted hazard ratio per SD increase (95% CI)P value
Pre-DM
1.48(1.21–1.79)
P < 0.001DM
1.30(1.06–1.60)
P = 0.011NGinsignificant
1.20(0.97–1.48)
P = 0.101Per SD increase in RDW-SD, as printed
Observational data: associations, not effects.
Further findings
| Outcome | aHR per SD increase (95% CI) | P value | |
|---|---|---|---|
| Primary outcome per SD increase in RDW-SD, overall DCM cohort | 1.29 (1.15–1.45) | P < 0.001 | |
| 0.512Adjusted hazard ratio per SD increase (log scale) |
Original publication
Association between RDW-SD and prognosis across glycemic status in patients with dilated cardiomyopathy. BMJ Open Diabetes Res Care. Published 14 November 2024. doi:10.
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