Association between glycaemia risk index ( glycaemia risk index (GRI) ) and diabetic retinopathy in type 2 diabetes: A cohort study
Authors' conclusion
In patients with type 2 diabetes, higher GRI is associated with an increased risk of incident DR. GRI has the potential to be a valuable clinical measure, which needs to be further explored in future studies.
Study context
- Population
- Adults with T2D without diabetic retinopathy (DR) at baseline, single centre in Shanghai, China, 2005–2019; GRI from baseline CGM data
- Participants
- 1,204 adults
- Exposure
- GRI quartiles
- Outcome
- Incident DR
- Follow-up
- Median 8.4 years
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Incident DR (multivariable-adjusted)
Each group vs GRI ≤14Hazard ratio (95% CI)
GRI 15 ≈28
1.05(0.74–1.48)
GRI 29 ≈47
1.33(0.96–1.84)
GRI > 47
1.53(1.11–2.11)
- Developed DR
- 301 patients
Observational data: associations, not effects.
Further findings
Incident DR per 1-SD increase in GRI
- Risk of DR increased by 20% per 1-SD increase in GRI, adjusted HR
- 1.20 (95% CI 1.07-1.33)
- After adjustment for confounders
Original publication
Association between glycaemia risk index ( GRI ) and diabetic retinopathy in type 2 diabetes: A cohort study. Diabetes Obes Metab. Published 23 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →