Continuous low serum levels of advanced glycation end products and low risk of cardiovascular disease in patients with poorly controlled type 2 diabetes
Main finding · Combined cardiovascular eventsResult — go to the resultHazard ratio 0.50 95% CI 0.28–0.87Authors' conclusion
Continuous low serum MG-H1 levels are associated with a low frequency of diabetes-related complications in patients with poorly controlled type 2 diabetes.
Study context
- Population
- Patients with poorly controlled T2D, mean HbA1c 10.1%
- Participants
- 138 patients
- Exposure
- Continuous low methyl-glyoxal-hydroimidazoline (MG-H1) vs others
- Outcome
- Combined cardiovascular events: heart disease, peripheral arterial disease, stroke and all-cause death
Main finding
Combined cardiovascular events
Hazard ratio
0.50
95% CI 0.28–0.87
P = 0.02
Continuous low MG-H1vs Others
HR 0.50 (95% CI 0.28–0.87); P = 0.02
As reported in the abstract
Observational data: associations, not effects.
Further findings
Combined cardiovascular events in patients without history of cardiovascular events
- The same relationship was observed in patients without a history of cardiovascular events
Original publication
Continuous low serum levels of advanced glycation end products and low risk of cardiovascular disease in patients with poorly controlled type 2 diabetes. Cardiovasc Diabetol. Published 23 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →